George W Muller Selected Research

CC-5079

11/2010	CC-5079: a small molecule with MKP1, antiangiogenic, and antitumor activity.
1/2006	The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity.

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George W Muller Research Topics

Disease

15	Neoplasms (Cancer) 01/2013 - 05/2002
4	Multiple Myeloma 09/2009 - 06/2003
2	Lymphoma (Lymphomas) 01/2013 - 09/2009
2	Melanoma (Melanoma, Malignant) 03/2009 - 07/2007
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 03/2009 - 01/2007
2	Neoplasm Metastasis (Metastasis) 03/2009 - 07/2007
1	Hypoxia (Hypoxemia) 03/2009
1	Anemia 03/2009
1	Chromosome Aberrations (Chromosome Abnormalities) 03/2009
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2009
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2009
1	Hematologic Neoplasms (Hematological Malignancy) 01/2007
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2006
1	Weight Loss (Weight Reduction) 03/2006
1	Colorectal Neoplasms (Colorectal Cancer) 01/2006

Drug/Important Bio-Agent (IBA)

7	Lenalidomide (CC 5013)FDA Link 01/2013 - 06/2003
5	pomalidomideIBA 01/2013 - 05/2002
5	Thalidomide (Thalomid)FDA Link 03/2006 - 05/2002
3	Immunomodulating AgentsIBA 08/2004 - 05/2002
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 10/2003
2	Interleukin-2 (IL2)IBA 01/2013 - 05/2002
2	CC-5079IBA 11/2010 - 01/2006
2	Pharmaceutical PreparationsIBA 03/2009 - 05/2002
2	CytokinesIBA 12/2003 - 10/2003
1	glycine amideIBA 11/2011
1	Dexamethasone (Maxidex)FDA LinkGeneric 03/2009
1	Phosphodiesterase InhibitorsIBA 01/2009
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 01/2009
1	CaspasesIBA 01/2009
1	Sorafenib (BAY 43-9006)FDA Link 07/2007
1	Histone Deacetylase InhibitorsIBA 01/2007
1	Tubulin ModulatorsIBA 01/2006
1	TubulinIBA 01/2006
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2006
1	Colchicine FDA LinkGeneric 01/2006
1	Interleukin-10 (Interleukin 10)IBA 08/2004
1	Hypnotics and Sedatives (Sedatives)IBA 10/2003
1	Antineoplastic Agents (Antineoplastics)IBA 02/2003
1	SelCID-3IBA 02/2003
1	Proteins (Proteins, Gene)FDA Link 02/2003
1	vadimezanIBA 01/2003

Therapy/Procedure

3	Therapeutics 09/2009 - 07/2007
1	Heterologous Transplantation (Xenotransplantation) 02/2003
1	Aftercare (After-Treatment) 01/2003